Anti Spasmodic
One type of antispasmodics is used for smooth muscle relaxation, especially in tubular organs of the gastrointestinal tract. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. Both of these drugs have general side effects and can worsen gastroesophageal reflux disease.
Mebeverine is a muscolotropic spasmolytic with a strong and selective action on the smooth muscle spasm of the gastrointestinal tract, particularly of the colon. It does not have the acetylecholine side effect commonly seen in an anticholinergic antispasmodic.

Product Description
Antispasmodic medicines are used to treat symptoms such as tummy pain and cramp (spasm). They are most used for symptoms of irritable bowel syndrome. The side-effects that may occur are usually minor.
Abdominal pain, bloating, cramping, diarrhea and constipation are commonly seen in clinical pharmacy practice. These symptoms cause significant discomfort and can impair a patient’s ability to perform their daily activities. Pharmacists are commonly asked to recommend products to reduce symptoms or even to cure their conditions.
Guidelines
Before taking this medication, tell your doctor or pharmacist if you are allergic to hyoscyamine , atropine, scopolamine, or phenobarbital; or to primidone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Clinical Research
Antispasmodics are a group (class) of medicines that can help to control some symptoms that arise from the gut (intestines) – in particular, gut spasm.
There are two main types, as follows.
Antimuscarinics such as: Dicycloverine, Hyoscine, Atropine, Propantheline
Smooth muscle relaxants such as: Alverine, Mebeverine, Peppermint oilAvailability
RENALSPAS: Directly relaxes smooth muscles
Potent relief from painful colics & spasmsIndication: Renal Colic, Gastrointestinal Colic, Spasmodic Dysmenorrhea BIO-SPAS: Negligible effects on mucous membrane
Relieves symptoms of DysmenorrheaIndication: Renal Colic, Gastrointestinal Colic, Spasmodic Dysmenorrhea, Biliary Colic